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FLASH GENE
Symbol MRPS30 contributors: mct/npt - updated : 12-07-2008
HGNC name mitochondrial ribosomal protein S30
HGNC id 8769
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   predominantly
Digestiveliver    
Hearing/Equilibriumear   highly
Lymphoid/Immunelymph node   highly
Reproductivefemale systemuteruscervix highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Muscularstriatumcardiac  
Muscularstriatumskeletal  
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • not showing any known motif or protein domain
  • specific to mitochondrial ribosomes not in prokaryotes
  • HOMOLOGY
    interspecies homolog to murine Mrps30
    homolog to E.Coli 30S subunit proteins
    intraspecies homolog to G-gallu proapoptotic protein p52
    Homologene
    FAMILY
  • ribosomal protein S30P family
  • CATEGORY regulatory , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    text mitochondrial ribosome
    basic FUNCTION
  • mitochondrial proteins biosynthesis
  • ribosomal structure and biogenesis
  • involved in cellular apoptotic signaling pathway
  • CELLULAR PROCESS cell life, cell death/apoptosis
    protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the small subunit (28S) of the mitochondrial ribosome, including two RNA molecules and 78 MRPs among which 31 proteins for the small subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to estrogen receptor positive breast cancer with good prognosis
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS