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FLASH GENE
Symbol COQ7 contributors: mct/npt - updated : 07/11/2008
HGNC name coenzyme Q7 homolog, ubiquinone (yeast)
HGNC id 2244
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveesophagus   highly
Reproductivefemale systemuteruscervix highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three hydrophobic regions N terminal, central and C terminal
  • a putative discrimination of mitochondrial targeting sequence (hTTDISC)
    • HOMOLOGY
    interspecies homolog to yeast S.cerevisiae cat5p
    homolog to C.elegans longevity gene clk1
    Homologene
    FAMILY
  • di-iron containing oxidases/hydroxylases family
    • CATEGORY enzyme , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    intracellular,nucleus
    basic FUNCTION
  • catalyzes the production of coenzyme Q (CoQ) in mitochondria
  • involved in ubiquinone biosynthesis and hence, is required for respiration and gluconeogenesis
  • functioning as a hydroxylase
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism carbohydrate
    signaling
    gluconeogenesis
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS