basic FUNCTION
| phosphatidylinositol-4-phosphate-5 kinase, type 1 alpha, putatively involved in membrane ruffle formation |
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playing a role in regulating stress-induced apoptosis |
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activation of KIF2A is not sufficient but is essential for the function of PIP5K1A |
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PIP5K1A and PIP5K1B may coordinately and/or redundantly function in the maintenance of sperm number and morphology during spermatogenesis |
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cytosolic PIP5K1A has been implicated in several cellular events like endocytosis, membrane ruffling and migration; the nuclear pool has been shown to be involved in pre-mRNA splicing events |