protein
| binding to synaptosome associated proteins SNAP23 and SNAP25 by their heptad repeats |
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interacting with TRAK1 and TRAK2 |
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interacting with RRBP1 |
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binding to unpolymerized tubulin |
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critical role of KIF5B-SYBU-mediated axonal transport in the maintenance of presynaptic function and regulation of synaptic plasticity |
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interaction between the cargo-binding domain of kinesin-1 heavy chain KIF5B and the membrane-associated SNARE proteins SNAP25 and SNAP23 (Morton 2010) |
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directly interact with syntabulin (GOLSYN) to mediate anterograde axonal transport of syntaxin-1 containing synaptic vesicles and mitochondria (Morton 2010) |
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requires ensconsin MAP7 for its primary function of organelle transport |
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KIF5B is required for the forward transport and axonal function of SCN10A, suggesting a mechanism for axonal accumulation of SCN10A in inflammatory pain |
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KIF5B directly binds to ankyrin-G (ANK3) to transport Nav channels into axons |
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ZFYVE27 interact with other hereditary spastic paraplegia-related proteins including myelin proteolipid protein 1 (PLP1), atlastin-1 (ATL1), REEP1, REEP5 (similar to REEP1), KIF5A, KIF5B, KIF5C |
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MAP7 cooperates with its binding partner KIF5B during interphase to trigger centrosome separation |
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PLCL1 and GABARAP function in a complex to regulate KIF5B-mediated insulin secretion, providing new insights into insulin exocytic mechanisms |