basic FUNCTION
| controling negatively cell growth |
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may negatively regulate sex steroid hormone action in bone formation |
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play important roles in spermatogenesis, embryonic dorsoventral patterning, osteogenesis, T-cell activation, and learning and memory |
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act primarily as transcriptional repressors in several signaling pathways |
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implicated in transcription in the nucleus and cytoplasmic mRNA deadenylation and turnover |
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involved in the general mechanism of mRNA decay by mediating mRNA deadenylation through interaction with CNOT8 and a general RNA-binding protein, PABPC1 |
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mediates the recruitment of CNOT8 to the target of CPEB3 and elicits deadenylation and decay of the mRNA |