basic FUNCTION
| might target cytosolic protein aggregates for autophagic degradation |
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as well as SQSTM1, is required for formation and autophagic degradation of cytoplasmic ubiquitin-positive inclusions |
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required for autophagic degradation of SQSTM1-associated ubiquitinated proteins |
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inclusions phosphatidylinositol 3-phosphate-binding protein, central to the selective elimination of aggregated proteins ( |
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may plays a key role in selective macroautophagy by bridging cargo to the molecular machinery that builds autophagosomes |
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