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FLASH GENE
Symbol POLR2D contributors: mct/npt - updated : 28-04-2005
HGNC name polymerase (RNA) II (DNA directed) polypeptide D
HGNC id 9191
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
Lymphoid/Immunelymph node    
Reproductivefemale systemuteruscervix  
Urinarybladder    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • eukaryotic RPB4 RNA polymerase subunit family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • polymerase II, DNA directed
  • potential role for the heterodimer (POLR2G/POLR2D) in binding and stabilizing the nascent RNA transcript (Meka 2005)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • with POLR2G, form a heterodimer that protrudes from the 10-subunit core of the enzyme (Meka 2005)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS