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FLASH GENE
Symbol SCAMP1 contributors: mlc/np - updated : 05-11-2007
HGNC name secretory carrier membrane protein 1
HGNC id 10563
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineneuroendocrinepituitary  highly
Nervousbrain   highly
Respiratoryrespiratory tracttrachea  highly
Urinarybladder   highly
Visualeye   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four putative transmembrane segments (4TM)
  • a serie of motifs including a calcium binding domain, a leucine zipper and two zinc finger domains
  • cytoplasmic N-terminal sequences with NPF repeats
  • a cytoplasmic tail
  • HOMOLOGY
    interspecies homolog to murine Scamp1
    Homologene
    FAMILY SCAMP family of proteins
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • involved in cell surface recycling
  • may function at the same site during vesicular transport rather than in separate pathways
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • widely distributed constituent of post-Golgi membranes
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS