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FLASH GENE
Symbol POLI contributors: npt/ - updated : 03-10-2006
HGNC name polymerase (DNA directed) iota
HGNC id 9182
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   lowly
Endocrinepancreas   highly
Lymphoid/Immunethymus    
Nervousspinal cord    
Reproductivefemale systemovary   
 male systemtestis  highly
 male systemprostate   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage predominantly, in postmeiotic round spermatids
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to yeast S.cerevisiae RAD30,B
Homologene
FAMILY
  • DNA polymerase type-Y family
  • CATEGORY enzyme , DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm
    basic FUNCTION
  • low fidelity and error prone, DNA polymerase promoting replication by incorporation deoxynucleotides opposite and bypassing DNA lesions, inducing somatic hypermutation in immunoglobulin genes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS