basic FUNCTION
| potentially involved in cell adhesion |
|
may play a role in lymphocyte activation |
|
inducing the production of TNFalpha from macrophage cells |
|
playing a role in the pathophysiology of clonal myeloid diseases |
|
not only contributes to host responses through the induction of proinflammatory cytokines but also directly affects specific immunity by differentiating monocytes into macrophage-like cells |
|
may be playing a role in inflammatory bowel diseases |
|
IL32 may play an important role in inflammatory responses and pancreatic cancer growth |
|
IL32 is induced by microbial ligands through TLR-mediated innate signaling pathways, suggesting an important role of corneal epithelium in inflammatory disease |
|
proinflammatory cytokine that participates in responses to viral infection |
|
multifaceted cytokine with a role in infections, autoimmune diseases, and cancer, and it exerts diverse functions, including aggravation of inflammation and inhibition of virus propagation |
|
critical regulator of endothelial cell (EC) functions, and also possesses angiogenic properties |
|
role for this versatile cytokine in pulmonary arterial hypertension and neoplastic diseases |
|
IL32 is involved in the pathogenesis of airway inflammation |
|
is known to act as a proinflammatory cytokine and is likely involved in several chronic inflammatory diseases |
|
IL32 is a molecular link between in keratinocytes (KCs) and Langerhans cells (LCs)in healthy skin, provoking LC migration from the epidermis to the dermis prior to their migration to the draining lymph nodes |
|
is a cytokine involved in proinflammatory immune responses to bacterial and viral infections |
|
act as a potent inducer of cell migration in several types of cancer |
|
cytokine associated with higher risk of cardiovascular diseases in inflammatory environments |
|
has a critical role in the pathogenesis of Nonalcoholic fatty liver disease (NAFLD) |