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FLASH GENE
Symbol AKAP4 contributors: mct/npt - updated : 03-09-2008
HGNC name a kinase (PRKA) anchor protein 4
HGNC id 374
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion sperm
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
secondary structure an amphipathic helix binding domain
HOMOLOGY
Homologene
FAMILY
  • AKAP110 family
  • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule
    text sperm fibrous sheath
    basic FUNCTION
  • a kinase (PRKA regulatory subunit RIIA) anchor protein tethering the enzyme near its physiological substrate(s), involved in sperm-motility
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS