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FLASH GENE
Symbol CDS1 contributors: mct/npt - updated : 28/10/2008
HGNC name CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
HGNC id 1800
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveintestinesmall intestine   
Endocrineparathyroid   highly
Reproductivefemale systemovary   
 male systemtestis   
 male systemprostate   
Urinarykidney   highly
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Epithelialsecretoryglandularendocrine 
Epithelialsensoryvisualphotoreceptor layer 
Muscularstriatumcardiac  
Nervouscentral   
Nervousperipherous   
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
Nervousneuron
Visualcone photoreceptor
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text placenta, fetal kidney, lung, brain and liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three putative membrane-spanning domains
  • HOMOLOGY
    interspecies homolog to C.elegans c33h5.18
    homolog to E.coli cds
    homolog to yeast cds
    homolog to Drosophila cds
    intraspecies homolog to cds2
    homolog to reticulum endothelial
    Homologene
    FAMILY
  • CDS family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,nuclear envelope
    basic FUNCTION
  • regulator of cellular phosphatidylinositol content
  • diacylglycerol cholinephosphotransferase (converting phosphatidic acid to CDP-diacylglycerol)
  • playing a role in phototransduction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling signal transduction , sensory transduction/vision
    phospholipid biosynthesis
    a component
  • involved in phosphoinositide mediated signaling pathway
  • INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
  • Mg2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS