motifs/domains
| N-terminal SKICH domain of unknown structure (AA 1–127), |
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an extended central coiled coil domain containing a leucine zipper motif (AA 140–420) |
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a C2H2-type zinc finger structure and this zinc finger in complex with mono-ubiquitin uncovers a unique zinc finger-binding mode for ubiquitin |
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a noncanonical LIR motif providing specificity for MAP1LC3C |
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a LIM-like C terminal domain |
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myosin tail |
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mutiple phosphorylation sites |
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a C-terminal ubiquitin-binding Zn finger domain (ZnF, AA 421–446) |
SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,Golgi
|
| intracellular,cytoplasm,cytosolic,vesicle
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| intracellular,cytoplasm,cytoskeleton
|
| intracellular,nucleus,nucleoplasm,nuclear bodies,PML
|
| intracellular,nuclear envelope
|
text
| expressed in the nuclear domain (ND) 10 (POD (PML) promyelocytic oncogenic domain or Kr bodies |
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with TAX1BP1 and myosin VI are present at the trans side of the Golgi complex, and on vesicles in the perinuclear region (Morriswood 2007) |