Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol VNN1 contributors: - updated : 05-05-2006
HGNC name vanin 1
HGNC id 12705
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
 thymus    
Digestiveintestinesmall intestine   
 liver    
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Lymphoid    
Muscularstriatumskeletal  
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immunelymphocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
putative GPI anchored cell surface molecule,containing a leader peptide and a putative GPI-cleavage motif
conjugated GlycoP
HOMOLOGY
interspecies ortholog to murine Vnn1
ortholog to Drosophila Vanin-like
intraspecies homolog to biotinidase
Homologene
FAMILY
  • carbon-nitrogen hydrolase family
  • vanin subfamily
  • CATEGORY adhesion , enzyme , regulatory
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
    text
  • secreted
  • membrane-associated protein by a GPI-anchor
  • basic FUNCTION
  • involved in lymphocyte migration in cell adhesion and in the colonization of the thymus by hematopoietic precursor cells
  • regulation of Sertoli cells
  • pantetheinase activity playing a role in oxidative-stress response
  • hydrolyzing specifically one of carboamide linkages in D-pantetheinase thus recycling pantothenic acid
  • ectoenzyme
  • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS reproduction/sex
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS