Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PAPSS2 | contributors: npt/mct - updated : 10-10-2016 |
HGNC name | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
HGNC id | 8604 |
|
EXPRESSION |
Rna function | the most significant levels of mRNA were found in condensing and proliferating chondrocytes |
Type | restricted |
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
physiological period | pregnancy |
Text | placenta, major variant in growth plate cartilage |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
intraspecies | homolog to PAPSS1 (77 p100) |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic | |
text |
basic FUNCTION | |
| |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | locomotion |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
|
cell & other |
REGULATION |
induced by | during chondrogenesis |
Other | regulated by extracellular signal-regulated protein kinase, protein kinase C, and p38 kinase, signaling molecules known to regulate chondrogenesis |
ASSOCIATED DISORDERS |
corresponding disease(s) | SEMD4 , BCYM4 |
Other morbid association(s) |
|
Susceptibility | to osteoarthritis(minor role in japanese) |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |