Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | NDUFB6 | contributors: npt/mct - updated : 24-11-2020 |
HGNC name | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
HGNC id | 7701 |
|
EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria,inner | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,nucleus,nucleoplasm |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
activated by | thyroid hormones |
ASSOCIATED DISORDERS |
corresponding disease(s) |
related resource | MITOP database |
Susceptibility | to age-dependent insulin resistance |
Variant & Polymorphism other | rs629566 G/G genotype exhibited higher muscle NDUFB6 expression, but is associated with reduced expression in elderly subjects, and degree of DNA methylation correlated negatively with muscle NDUFB6 expression, which in turn was associated with insulin sensitivity (Ling 2007) |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |