SUBCELLULAR LOCALIZATION
| plasma membrane
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| intracellular
|
| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,endoplasmic reticulum
|
| intracellular,cytoplasm,organelle,endosome
|
| intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
|
| intracellular,nucleus
|
basic FUNCTION
| immediate early gene in regenerating liver, involved in cellular growth of the liver |
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may play a role in the development and maintenance of differentiating epithelial tissues |
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implicated in promoting cell growth, differentiation, and tumor invasion |
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enhancing cell proliferation, cell motility and invasive activity, and promotes cancer metastasis |
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may be a significant regulator in the development and metastasis of a variety of cancer types |
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may contribute to tumor development by the downregulation of p53 by a negative feedback mechanism |
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trimer formation is essential for PRL1-mediated cell growth and migration |
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play an important role in the regulation of neural function |
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PHF3 and/or PTP4A1 might play a functional role in alcohol dependence |
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PTP4A1, PTP4A2, PTP4A3 are key contributors to metastasis in several human cancers |