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FLASH GENE
Symbol DNAH17 contributors: mct - updated : 26-08-2019
HGNC name dynein, axonemal, heavy polypeptide 17
HGNC id 2946
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis    Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivespermatid Homo sapiens
Reproductivespermatocyte Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY motor/contractile
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton,microtubule
basic FUNCTION
  • outer dynein arm heavy chain having ATPase activity
  • involved in intracellular movement of organelles and vesicles or in the orientation of the mitotic spindle apparatus
  • CELLULAR PROCESS cell cycle, division
    cell communication
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component axonemal constituent (outer arm)
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other interacting with microtubules
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) SPGF39
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
  • could be a promising biomarker for tumor thrombosis in HCC patients
  • Therapy target
    ANIMAL & CELL MODELS