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FLASH GENE
Symbol OAS3 contributors: - updated : 25-03-2006
HGNC name 2'-5'-oligoadenylate synthetase 3, 100kDa
HGNC id 8088
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue  highly
Reproductivefemale systembreastmammary gland highly
 female systemuterus  highly
Skin/Tegumentskin   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticmonocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • Gas-like domain
  • IRF1 like domain
  • GAS domain
  • SRE domain
  • mono polymer monomer , dimer
    HOMOLOGY
    Homologene
    FAMILY 2'-5' oligoadenylate synthetase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,microsome
    basic FUNCTION
  • involved in inhibition of cellular protein synthesis and in viral infection resistance
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    nucleotide
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by interferon induced (IFN1)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS