Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
| fusion
|  
|  
|  
|
with NUP98 in a paediatric acute T cell lymphoblastic leukaemia with t(11;18)(p15;q12) | tumoral
| somatic mutation
|  
|  
|  
|
cause gain of function, are associated with myeloid leukemic transformation and convey poor prognosis in myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML) | tumoral
| somatic mutation
|  
|  
|  
|
associated with CSF3R and/or ASXL1 mutation in chronic neutrophilic leukemia (CNL) | tumoral
| somatic mutation
|  
|  
|  
|
recurrent SETBP1 mutations (p.Gly870Ser alteration abrogated a site for ubiquitination) in atypical chronic myeloid leukemia 6) | |