basic FUNCTION
| minor histocompatibility antigen which may induce graft rejection of male stem cell grafts |
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lacking detectable demethylase activity, compensates for the loss of KDM6A in regulating Brachyury expression |
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catalyzes demethylation of H3K27 peptides, analogously to KDM6B and KDM6A, but with reduced activity, due to point substitutions involved in substrate binding |
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NKX3.1-G9a-UTY transcriptional regulatory network is essential for prostate differentiation, and likely disruption of such a network predisposes to prostate cancer |
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both KDM6A and UTY function as dose-dependent suppressors of urothelial bladder cancer (UBC) development |