basic FUNCTION
| modulating cell fate and cell behavior during vertebrate development |
|
playing a role in the development and progress of gastric, esophageal and pancreatic cancer |
|
being a ligand for members of the frizzled family of seven transmembrane receptors |
|
involved in a short-range paracrine signal required for WNT-pathway responses and programmed cell death in the vascular endothelial cells of the temporary hyaloid vessels of the developing eye |
|
modulates several important signaling pathways in the lung |
|
Wnt pathway ligand, produced by macrophages to stimulate repair and regeneration |
|
stimulate epithelial responses during kidney development |
|
key regulator of the tissue architecture that establishes a functional physiologically active mammalian kidney |