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FLASH GENE
Symbol FARSA contributors: np - updated : 12-12-2007
HGNC name phenylalanyl-tRNA synthetase, alpha subunit
HGNC id 3592
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
 mouthtongue   
Lymphoid/Immunespleen    
Reproductivemale systemprostate   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to yeast S.cerevisiae phenylalanine-tRNA synthetase
Homologene
FAMILY
  • aminoacyl-tRNA synthetase (class-II) family
  • Phe-tRNA synthetase alpha chain subfamily 2
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • may be involved in pathogenesis, phenylalanyl-tRNA aminoacylation
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterodimerizing with FARSB in chronic myeloid leukemia cells
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral fusion      
    with FARSB in chronic myeloid leukemia cells
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS