basic FUNCTION
| may be involved in modulating chromatin formation |
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contributing to regulation of cell proliferation |
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participating in DNA replication |
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cofactor for the import of histones H2A and H2B, a chromatin assembly factor and a mitotic factor involved in regulation of bud formation (Calvert 2008) |
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cooperates with EP300 in eviction of the acetylated histones from the chromatin template (Sharma 2008) |
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promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions (Andrews 2010) |
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histone chaperone protein suspected to be involved in the dynamical regulation of the histone H2A-H2B hetero-dimer (Okuwaki 2010) |
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with NAP1L4 mediated nucleosome formation (Okuwaki 2010) |
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possess a significantly greater nucleosome disassembly activity than NAP1L4, suggesting that NAP1L1 and NAP1L4 may play distinct roles in the regulation of histone dynamics (Okuwaki 2010) |
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is required for cohesin release and sister chromatid resolution during mitosis |
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NAP1L1 binding to cohesin is cell-cycle regulated and increases during G2/M phase |