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FLASH GENE
Symbol CKS2 contributors: - updated : 15-01-2004
HGNC name CDC28 protein kinase regulatory subunit 2
HGNC id 2000
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
binding six kinase subunits
mono polymer homomer , tetramer
HOMOLOGY
interspecies homolog to yeast S.pombe CKS2
Homologene
FAMILY CKS family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • inhibiting the activation of cyclin A/CDK2 kinase
  • involved in the G1/S transition of the cell cycle
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS