Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | DPEP1 | contributors: mct - updated : 28-03-2019 |
HGNC name | dipeptidase 1 (renal) |
HGNC id | 3002 |
|
EXPRESSION |
Type | restricted |
cell lineage
cell lines
| fluid/secretion
| sreum, urine | |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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| |
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secondary structure | eight alplha helix and beta sheet pairs per subunit |
conjugated | GlycoP , LipoP , MetalloP |
mono polymer | homomer , dimer |
isoforms | Precursor | a signal peptide from the 1st to the 16th aa |
HOMOLOGY |
Homologene |
FAMILY | peptidase M19 family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | extracellular |
plasma membrane,junction | |
intracellular | |
intracellular,cytoplasm | |
intracellular,nucleus | |
text | |
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basic FUNCTION | |
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CELLULAR PROCESS | protein, degradation |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | lipid/lipoprotein |
signaling |
metabolism of glutathione and its conjugates |
a component | homodimer disulfide-linked |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, cofactor, |
two ions Zn2+ |
protein |
cell & other |
REGULATION |
inhibited by | by EEDQ and dansyl-ethylenediamine |
cilastatin |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
Mbd1 deficient mice |