basic FUNCTION
| major multifunctional nucleolar phosphoprotein characterized by unique tripartite function within each domain |
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performing activities i.e. a specific DNA helicase and DNA-dependent ATPase |
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involved in binding of glucocorticoid receptor in the nucleolus |
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playing a role in posttranscriptional control of MMP9 expression |
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general role for nucleolin in gene regulation and it is a novel factor involved in regulation of KLF2 expression |
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may be involved in the dynamics of human papillomavirus genome in cells ( |
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may induce the MYC G-quadruplex formation that functions as a transcriptional repressor for MYC (Gonzalez 2009) |
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major multifunctional nucleolar phosphoprotein characterized by unique tripartite function within each domain |
|
performing activities i.e. a specific DNA helicase and DNA-dependent ATPase |
|
involved in binding of glucocorticoid receptor in the nucleolus |
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may induce the MYC G-quadruplex formation that functions as a transcriptional repressor for MYC |
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playing a role in posttranscriptional control of MMP9 expression |
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may be involved in the dynamics of human papillomavirus genome in cells ( |
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plays important roles in chromatin structure, rDNA transcription, rRNA maturation, nucleocytoplasmic transport, and ribosome assembly |
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important negative regulatory role for nucleolin in the apoptosis of endothelial cells, likely involving the BAX pathway |
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an essential downstream effecter of Hsp70 in the protection of cardiomyocytes against oxidative stress-induced apoptosis |
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major nucleolar protein that has been shown to be overexpressed in rapidly dividing cells and plays an essential role in cell proliferation and survival |
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major nucleolar protein that has been shown to be overexpressed in rapidly dividing cells and plays an essential role in cell proliferation and survival |
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most abundant nucleolar phosphoprotein of eukaryotic cells, is known primarily for its role in ribosome biogenesis and cell proliferation |
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HNRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition |
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is required for nucleosome disruption surrounding a double-strand break (DSB) |
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plays a critical role in DNA repair by promoting partial nucleosome disruption and permitting subsequent recruitment of DNA repair factors |
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is a chromatin-remodeling factor that facilitates nucleosome disassembly and efficient DSB repair |
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