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FLASH GENE
Symbol TMEM138 contributors: mct - updated : 28-03-2012
HGNC name transmembrane protein 138
HGNC id 26944
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain     Homo sapiens
Urinarykidney     Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • both TMEM138 and TMEM216 are required for ciliogenesis
  • might mark vesicles en route to the base of cilium, which is known to be crucial for ciliary assembly
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • possible functional dependence on TMEM216 for trafficking TMEM138 and associated proteins
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) JBTS16
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS