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FLASH GENE
Symbol NOL9 contributors: mct - updated : 30-06-2011
HGNC name nucleolar protein 9
HGNC id 26265
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,nucleolus
basic FUNCTION
  • displays polynucleotide kinase activity
  • its polynucleotide kinase activity is required for efficient generation of the 5.8S and 28S rRNAs from the 32S precursor
  • nucleolar polynucleotide kinase with a role in rRNA processing
  • is a 5 prime end-specific RNA/DNA kinase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • LAS1L interacts with PELP1 and WDR18, the mammalian homologues of the budding yeast Rix1 complex, along with NOL9 and SENP3, to form a novel nucleolar complex that cofractionates with the 60S preribosomal subunit
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS