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FLASH GENE
Symbol EMC3 contributors: mct - updated : 22-03-2016
HGNC name ER membrane protein complex subunit 3
HGNC id 23999
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY DNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum
basic FUNCTION
  • is part of the endoplasmic reticulum-associated secretory pathway
  • EMC1, EMC3, EMC8, EMC9 are key factors in the biogenesis of multi-pass transmembrane proteins, including RHO, and loss causes retinal degeneration
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS