protein
| cooperates with histone deacetylases (HDACs) to suppress RARA, probably by associating with HDAC |
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associated with histone demethylase KDM1A and suppressed KDM1A-enhanced ESR1 activity |
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associated with KDM1A, functions as an ESR1 corepressor, implicating a potential antitumor target in ESR1-positive breast cancer |
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CACUL1/CAC1 is a positive regulator of the NFE2L2 pathway |
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directly associates with AR and suppresses AR transcriptional activity |
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CACUL1 is a novel regulator that negatively controls TP53 activity through the regulation of PML SUMOylation |
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CACUL1 tightly regulates PPARG signaling through the mutual opposition between SIRT1 and KDM1A, providing insight into its potential use for anti-obesity treatment |