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FLASH GENE
Symbol RNASEK contributors: SGE - updated : 06-03-2008
HGNC name Ribonuclease, RNase K
HGNC id 33911
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one SANT domain
  • conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to murine Rnasek (100.0pc)
    homolog to dog RNASEK (94.9pc)
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION endoribonuclease that preferentially cleave ApU and ApG phosphodiester bonds, while it hydrolyze UpU bonds at a lower rate
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS