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FLASH GENE
Symbol SLC25A42 contributors: mct - updated : 06-11-2020
HGNC name solute carrier family 25, member 42
HGNC id 28380
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland   highly
Lymphoid/Immunelymph node   highly
Nervousbrainforebraincerebral cortex highly
Olfactory (smell)olfactory bulb   highly
Reproductivefemale systemuteruscervix highly
Urinarykidney   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three solcar repeats
    • HOMOLOGY
    Homologene
    FAMILY
  • mitochondrial carrier family
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    intracellular,nucleus
    basic FUNCTION
  • imports coenzyme A into mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and ADP (Fiermonte 2009)
  • might likely exchange mitochondrial dephosphoCoA (dPCoA) with cytosolic ADP, allowing coenzyme A (CoA) to be produced both in the matrix by coenzyme A synthase (COASY) and in the cytosol by the monofunctional dPCoA kinase
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ADP binding
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS