basic FUNCTION
| may be part of subnuclear protein complexes involved in diverse processes, such as transcription and splicing |
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mediates the membrane trafficking of GUCY2D out of the ER of cells |
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photoreceptor guanylate cyclase-binding protein required for the stable expression and membrane vesicle trafficking of GUCY2D and GUCY2F in photoreceptors |
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crucial for guanylate cyclase expression and trafficking in photoreceptors |
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chaperone trafficking protein, implicated in the stable expression of guanylate cyclase in photoreceptor cells |
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essential for normal expression of retinal membrane guanylyl cyclase (GUCY2D) in photoreceptor cells, and blocks GUCY2D catalytic activity and stimulation by guanylyl cyclase-activating proteins (GCAPs) |
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may play likely an important role in the normal functioning of epithelial cells limited in the CNS |
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complex function of RD3 in photoreceptors, and RD3 - guanylate kinase interaction may also play a role in other cellular systems, while the GC - RD3 interaction is exclusive to photoreceptors |