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FLASH GENE
Symbol DEFB104B contributors: KTN/npt - updated : 26-01-2009
HGNC name defensin, beta 104B
HGNC id 26165
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  predominantly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a 22 aa signal peptide
  • six-cysteine motif characteristic for a ß-defensin (García 2001)
  • HOMOLOGY
    Homologene
    FAMILY
  • beta-defensin family
  • CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • having antimicrobial and chemoattractant activities (García 2001)
  • having synergistic effects with lysozyme and DEFB103 (García 2001)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by PKC (protein kinase C) mediation in airway epithelial cells (García 2001)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS