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FLASH GENE
Symbol CEACAM19 contributors: npt - updated : 05-03-2010
HGNC name carcinoembryonic antigen-related cell adhesion molecule 19
HGNC id 31951
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue   
Endocrinepancreas    
Urinarybladder    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two Immunoglobulin-like (Ig-like) transmembrane domains, present in most of the CEA proteins
  • one highly conserved domain of eukaryotic translation initiation factors
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Ceacam19
    Homologene
    FAMILY
  • CEA multigene family
  • immunoglobulin superfamily
  • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    repressed by dexamethasone in BT-474 breast cancer cell lines
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in ovarian cancers which are clinically more aggressive
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS