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FLASH GENE
Symbol DNTTIP2 contributors: - updated : 03-04-2006
HGNC name deoxynucleotidyltransferase, terminal, interacting protein 2
HGNC id 24013
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine  highly
Endocrinepancreas   highly
Lymphoid/Immunethymus   highly
Respiratoryrespiratory tractlarynx  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two ESR1 binding regions
  • C-terminal ESR1 binding region is increased by estrogen while the binding of ERBP region at N-terminus is not affected by estrogen
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY receptor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION enhancing the transcriptional activity of ESR1
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • bound to PPARG, RXRA, and ESR2
  • interacting with the DNA binding domain and the hinge region of ESR1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS