Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol AAMDC contributors: mct - updated : 11-06-2021
HGNC name adipogenesis associated Mth938 domain containing
HGNC id 30205
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   moderately
 vessel   highly
Digestivepancreas exocrine   moderately
Reproductivefemale systembreastmammary gland highly
 female systemovary  moderately
 male systemprostate  moderately
 male systemtestis  moderately
Visualeye   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscular    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • regulates the expression of several metabolic enzymes involved in the one-carbon folate and methionine cycles, and lipid metabolism
  • AAMDC-RABGAP1L complex could play a role in the regulation of vesicle trafficking, potentially altering the recycling of small G proteins and thus remodeling the cancer signaling network
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • AAMDC can interact with the RabGTPase-activating protein RABGAP1L, and AAMDC, RABGAP1L, and RAB7A colocalize in endolysosomes
  • cell & other
    REGULATION
    Other is post-transcriptionally regulated through alternative polyadenylation (APA) and microRNAs
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS