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FLASH GENE
Symbol CELA2A contributors: np/ - updated : 25-07-2005
HGNC name chymotrypsin-like elastase family, member 2A
HGNC id 24609
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas   specific
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal peptide
  • an activation petptide
  • a peptidase S1 domain
  • isoforms Precursor of a 241aa mature enzyme
    HOMOLOGY
    interspecies ortholog to rattus Ela2
    Homologene
    FAMILY
  • serine protease family
  • peptidase S1 family
  • elastase subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
    text secreted as a zymogen
    basic FUNCTION
  • pancreatic elastase activity
  • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with CPA1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS