Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CYB5R2 contributors: - updated : 25-07-2005
HGNC name cytochrome b5 reductase 2
HGNC id 24376
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   moderately
Nervousbrain   moderately
Reproductivemale systemtestis  predominantly
Respiratorylung   moderately
 respiratory tractlarynx  moderately
Skin/Tegumentskin   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two FAD-binding motifs
  • three NADPH-binding motifs
  • binding motifs for heme
  • HOMOLOGY
    interspecies ortholog to chicken CYB5R
    Homologene
    FAMILY
    CATEGORY enzyme , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism and in erythrocyte, methemoglobin reduction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism drug , lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide, other,
  • FAD
  • NADPH
  • heme
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS