Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TOR2A contributors: - updated : 21-06-2005
HGNC name torsin family 2, member A
HGNC id 11996
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland   moderately
Lymphoid/Immunespleen   highly
Nervousbrain   moderately
Reproductivefemale systemovary  highly
Respiratorylung   moderately
Urinarybladder   highly
cell lineage
cell lines
fluid/secretion blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an ATP-binding domain
  • HOMOLOGY
    interspecies homolog to murine Tor2a
    Homologene
    FAMILY
    CATEGORY chaperone/stress , enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • acting as a GTP cyclohydrolase I
  • acting as a nucleoside-triphosphatase
  • involved in chaperone cofactor dependent protein folding
  • CELLULAR PROCESS protein, post translation, folding
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS