protein
| interacts with MET(bound to MET tyrosine kinase domain through its SPRY domain, in both the absence and the presence of HGF) |
|
SPSB1 and SPSB4 bind strongly to both Par-4 and DDX4 peptides |
|
SPSB1, SPSB2, SPSB4 can induce the subcellular redistribution of NOS2 from dense regions to diffused expression in a SOCS box-dependent manner |
|
RAS enhances TGFB1 signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1 |
|
SPSB1 and SPSB2 are key physiological regulators of NOS2 |
|
SPSB1 enhances ovarian cancer cell survival by destabilizing CDKN1A |
|
paralogs SPSB1 and SPSB4, but not SPSB2 and SPSB3, can interact with and facilitate NR1D1 ubiquitination and degradation and regulate circadian clock periodicity |