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FLASH GENE
Symbol OTUD4 contributors: - updated : 26-03-2007
HGNC name OTU domain containing 4
HGNC id 24949
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node    
 thymus    
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose   
Muscular    
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductiveoocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one OTU domain
  • one tudor domain
  • HOMOLOGY
    interspecies ortholog to murine Otud4
    ortholog to rattus otud4
    Homologene
    FAMILY OTU-like cysteine protease family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • playing an essential role for female fertility, germ cell division and differentiation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by OVOL1
    induced by by hiv-1 insertion
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS