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FLASH GENE
Symbol GJC3 contributors: ktn/npt - updated : 05/01/2009
HGNC name gap junction protein, gamma 3, 30.2kDa
HGNC id 17495
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveliver   highly
 pancreas exocrine   moderately
Nervousbrain    
 nervespinal nervesciatic  
 spinal cord    
Reproductivefemale systembreastmammary gland lowly
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal highly
Nervouscentral   
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer hexamer
HOMOLOGY
interspecies homolog to rattus Gje1 (66.5 pc)
homolog to murine Gje1 (66.2 pc)
Homologene
FAMILY
  • connexin family
  • gamma-type subfamily
  • CATEGORY regulatory , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,gap
    text
  • myelin sheath
  • multi-pass membrane protein
  • basic FUNCTION
  • participating in the formation of active channels when coexpressed with Cx32
  • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS cell to cell transport
    text materials of low molecular weight diffuse from one cell to a neighboring cell
    PATHWAY
    metabolism
    signaling
    a component
  • connexon composed of a hexamer of connexins
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS