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FLASH GENE
Symbol ENPP6 contributors: - updated : 02-03-2007
HGNC name ectonucleotide pyrophosphatase/phosphodiesterase 6
HGNC id 23409
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach    
Nervousnervecranial nerve   
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
an NPP domain with significant homology to NPP4, NPP5, and NPP7/alkaline sphingomyelinase
HOMOLOGY
interspecies homolog to murine Enpp6
Homologene
FAMILY ENPP family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • choline-specific glycerophosphodiester phosphodiesterase
  • hydrolyzes LPC to form monoacylglycerol and phosphorylcholin
  • having a specific role through the hydrolysis of polyunsaturated lysophosphatidylcholine, glycerophosphorylcholine, or sphingosylphosphorylcholine in kidney and brain
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    nucleotide metabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS