basic FUNCTION
| catalyzing the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes |
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showing an aldose bisphosphate synthase activity with glucose 1-phosphate, deoxyribose 1-phosphate, ribose 1-phosphate, glucose 6-phosphate, and mannose 1-phosphate as substrates, but little or no activity on mannose 6-phosphate, ribose 5-phosphate |
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identified as as glucose-1,6-bisphosphate synthase |
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enzyme responsible for the synthesis of the elevated concentrations of Glc-1,6-P2 in brain |
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is specialized for glucose 1,6-bisphosphate (G16P) synthase activity |