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FLASH GENE
Symbol TSEN2 contributors: mct/npt - updated : 26-03-2007
HGNC name tRNA splicing endonuclease 2 homolog (S. cerevisiae)
HGNC id 28422
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainhindbraincerebellumcerebellar cortex 
Visualeyeretina   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • catalytic C-terminal domain
  • HOMOLOGY
    interspecies homolog to murine Tsen2
    Homologene
    FAMILY
  • tRNA-intron endonuclease family
  • CATEGORY enzyme , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • requiring for cell growth and division, catalyzing the removal of introns, the first step in tRNA splicing
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PCH2B
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS