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FLASH GENE
Symbol PCBD2 contributors: - updated : 18-12-2006
HGNC name pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
HGNC id 24474
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer heteromer
HOMOLOGY
interspecies ortholog to C.elegans 1H529
intraspecies homolog to PCBD
Homologene
FAMILY
  • DCOH family
  • pterin-4-alpha-carbinolamine dehydratase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION stabilizing HNF1-alpha as a dimer
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component forming a 2:2 complex with HNF1 in vitro
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • forms a complex with HNF1-alpha and Mirk (Mirk/Dyrk1B is an arginine-directed serine/threonine protein kinase)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS