basic FUNCTION
| transcriptional regulator involved in development |
|
regulates the expression of NR4A2, a nuclear receptor that is associated with familial Parkinson's disease |
|
forkhead/wing helix transcription factor with a role in the specification of cells in retinogenesis and spinal neurogenesis |
|
is required for retinal ganglion cell distal axon patterning |
|
may have a non-cell-autonomous role critical for alveologenesis during lung development |
|
transcription factor involved in developing spinal cord and spinal neurogenesis, and implied important roles in the central nervous system (CNS) |
|
might play important roles in CNS pathophysiology after spinal cord injury (SCI) |
|
is a key regulator in a variety of biological processes during development |
|
plays an essential role in the genesis of horizontal and amacrine neurons from neural progenitors in the vertebrate retina |
|
FOXN4 exhibited substantial thymopoietic activity |
|
FOXN4, RORB and their downstream effector PTF1A, have been shown to be indispensable intrinsic regulators for the differentiation of amacrine and horizontal cells |