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FLASH GENE
Symbol PGBD3 contributors: mct - updated : 29-03-2021
HGNC name piggyBac transposable element derived 3
HGNC id 19400
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Urinarybladder    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
cytochrome c heme binding site
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,nucleoplasm,nuclear bodies
basic FUNCTION
  • transposase activity
  • ERCC6-PGBD3 fusion protein, like many other proteins that can cause POF, modulates or participates in DNA repair
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • ERCC6-PGBD3 fusion protein is important in both health and disease, and could play a role in Cockayne syndrome
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS